Description

Prima – Celiac Test (1 Test)

CELIAC DISEASE
Celiac Disease (CD), also known as “celiac sprue”, is a chronic inflammatory disorder of the small intestine, produced by the ingestion of dietary gluten products in susceptible people. It is a multifactorial disease, including genetic and environmental factors. Environmental trigger is represented by gluten while the genetic predisposition has been identified in the major histocompatibility complex region which causes the presence of specific antibodies against gluten and its components.
Celiac disease is not a rare disorder like previously thought, with a global prevalence around 1%. The reason of its under recognition is mainly referable to the fact that about half of affected people do not have the classic gastrointestinal symptoms, but they present nonspecific manifestations nutritional deficiency or have no symptoms at all.

GLUTEN, GLIADIN AND DGP
Gluten is a protein found in wheat, composed of glutenin and gliadin. It helps foods maintain their shape, acting as a
glue that holds food together. Gliadin is a peptide water-soluble component of gluten and it can pass through the intestinal
epithelium. Gliadin is the part of gluten responsible for Celiac Disease. DGP: Deamidated gliadin peptides are the
result of the action of Transglutaminase Enzyme and its detection could increase sensitivities, specificities and accuracies of celiac disease screening.

Tag: Test, celiac, gluten, gastro

Directions:

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Warnings:

ALWAYS READ THE LABEL. USE ONLY AS DIRECTED. IF SYMPTOMS PERSIST TALK TO YOUR HEALTHCARE PROFESSIONAL. THIS MEDICINE MAY NOT BE RIGHT FOR YOU. INCORRECT USE MAY BE HARMFUL. READ THE WARNINGS BEFORE PURCHASE. THE PHARMACIST RESERVES THE RIGHT TO NOT SUPPLY CONTRARY TO OUR PROFESSIONAL AND ETHICAL OBLIGATION.